BDBM50285231 3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzoyl)-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-cyclopentyl ester::CHEMBL66923

SMILES: COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1

InChI Key: InChIKey=JOOTZGPUMCZHLH-XMSQKQJNSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50285231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50285231 (3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzo...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H25NO10/c1-38-28(37)17-4-2-6-19(31)23(17)25(34)24-20(32)12-15(13-21(24)33)27(36)39-22-7-3-5-18(22)29-26(35)14-8-10-16(30)11-9-14/h2,4,6,8-13,18,22,30-33H,3,5,7H2,1H3,(H,29,35)/t18-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Pharmaceuticals					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				Bioorg Med Chem Lett 5: 2133-8 (1995) Article DOI: 10.1016/0960-894X(95)00361-V BindingDB Entry DOI: 10.7270/Q26T0JT4
					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50285231 (3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzo...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H25NO10/c1-38-28(37)17-4-2-6-19(31)23(17)25(34)24-20(32)12-15(13-21(24)33)27(36)39-22-7-3-5-18(22)29-26(35)14-8-10-16(30)11-9-14/h2,4,6,8-13,18,22,30-33H,3,5,7H2,1H3,(H,29,35)/t18-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Pharmaceuticals					Assay Description Inhibition of Protein kinase C eta expressed in Sf-9 cells				Bioorg Med Chem Lett 5: 2133-8 (1995) Article DOI: 10.1016/0960-894X(95)00361-V BindingDB Entry DOI: 10.7270/Q26T0JT4
					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50285231 (3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzo...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H25NO10/c1-38-28(37)17-4-2-6-19(31)23(17)25(34)24-20(32)12-15(13-21(24)33)27(36)39-22-7-3-5-18(22)29-26(35)14-8-10-16(30)11-9-14/h2,4,6,8-13,18,22,30-33H,3,5,7H2,1H3,(H,29,35)/t18-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Pharmaceuticals					Assay Description Inhibition of protein kinase C epsilon expressed in Sf-9 cells				Bioorg Med Chem Lett 5: 2133-8 (1995) Article DOI: 10.1016/0960-894X(95)00361-V BindingDB Entry DOI: 10.7270/Q26T0JT4
					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50285231 (3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzo...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H25NO10/c1-38-28(37)17-4-2-6-19(31)23(17)25(34)24-20(32)12-15(13-21(24)33)27(36)39-22-7-3-5-18(22)29-26(35)14-8-10-16(30)11-9-14/h2,4,6,8-13,18,22,30-33H,3,5,7H2,1H3,(H,29,35)/t18-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Pharmaceuticals					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				Bioorg Med Chem Lett 5: 2133-8 (1995) Article DOI: 10.1016/0960-894X(95)00361-V BindingDB Entry DOI: 10.7270/Q26T0JT4
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50285231 (3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzo...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H25NO10/c1-38-28(37)17-4-2-6-19(31)23(17)25(34)24-20(32)12-15(13-21(24)33)27(36)39-22-7-3-5-18(22)29-26(35)14-8-10-16(30)11-9-14/h2,4,6,8-13,18,22,30-33H,3,5,7H2,1H3,(H,29,35)/t18-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Pharmaceuticals					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				Bioorg Med Chem Lett 5: 2133-8 (1995) Article DOI: 10.1016/0960-894X(95)00361-V BindingDB Entry DOI: 10.7270/Q26T0JT4
					More data for this Ligand-Target Pair