BDBM50285468 {[(2S,3R,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphorylmethyl}-phosphonomethyl-phosphinic acid anion

SMILES: Cc1cn(C2CC(N=[N+]=[N-])C(COP([O-])(=O)CP([O-])(=O)CP([O-])([O-])=O)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=DGAUZSHUMUJTDF-UHFFFAOYSA-J

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50285468 ({[(2S,3R,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dih...) Show SMILES Cc1cn(C2CC(N=[N+]=[N-])C(COP([O-])(=O)CP([O-])(=O)CP([O-])([O-])=O)O2)c(=O)[nH]c1=O Show InChI InChI=1S/C12H20N5O11P3/c1-7-3-17(12(19)14-11(7)18)10-2-8(15-16-13)9(28-10)4-27-31(25,26)6-29(20,21)5-30(22,23)24/h3,8-10H,2,4-6H2,1H3,(H,20,21)(H,25,26)(H,14,18,19)(H2,22,23,24)/p-4	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 5: 2315-2320 (1995) Article DOI: 10.1016/0960-894X(95)00401-E BindingDB Entry DOI: 10.7270/Q2PG1S7P
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