BDBM50285661 2-{4-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-phenyl}-1H-benzoimidazole::CHEMBL85441

SMILES: C(COc1ccc(cc1)-c1nc2ccccc2[nH]1)CN1CCN(CC1)c1ccccc1

InChI Key: InChIKey=LSZYSKUEBVDYTO-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50285661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50285661 (2-{4-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-phenyl}...) Show SMILES C(COc1ccc(cc1)-c1nc2ccccc2[nH]1)CN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C26H28N4O/c1-2-7-22(8-3-1)30-18-16-29(17-19-30)15-6-20-31-23-13-11-21(12-14-23)26-27-24-9-4-5-10-25(24)28-26/h1-5,7-14H,6,15-20H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards cloned human Dopamine D3 receptor in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 5: 2547-2550 (1995) Article DOI: 10.1016/0960-894X(95)00447-2 BindingDB Entry DOI: 10.7270/Q20R9PCT
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50285661 (2-{4-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-phenyl}...) Show SMILES C(COc1ccc(cc1)-c1nc2ccccc2[nH]1)CN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C26H28N4O/c1-2-7-22(8-3-1)30-18-16-29(17-19-30)15-6-20-31-23-13-11-21(12-14-23)26-27-24-9-4-5-10-25(24)28-26/h1-5,7-14H,6,15-20H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to dopamine D3 receptor (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-012-0055-5 BindingDB Entry DOI: 10.7270/Q2959MG8
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50285661 (2-{4-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-phenyl}...) Show SMILES C(COc1ccc(cc1)-c1nc2ccccc2[nH]1)CN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C26H28N4O/c1-2-7-22(8-3-1)30-18-16-29(17-19-30)15-6-20-31-23-13-11-21(12-14-23)26-27-24-9-4-5-10-25(24)28-26/h1-5,7-14H,6,15-20H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	406	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to dopamine D2 receptor (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-012-0055-5 BindingDB Entry DOI: 10.7270/Q2959MG8
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50285661 (2-{4-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-phenyl}...) Show SMILES C(COc1ccc(cc1)-c1nc2ccccc2[nH]1)CN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C26H28N4O/c1-2-7-22(8-3-1)30-18-16-29(17-19-30)15-6-20-31-23-13-11-21(12-14-23)26-27-24-9-4-5-10-25(24)28-26/h1-5,7-14H,6,15-20H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	406	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards cloned human Dopamine D2 receptor in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 5: 2547-2550 (1995) Article DOI: 10.1016/0960-894X(95)00447-2 BindingDB Entry DOI: 10.7270/Q20R9PCT
					More data for this Ligand-Target Pair