BDBM50285993 6-(4-Fluoro-phenoxy)-3-(3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL99528

SMILES: CN(C)C(=O)n1cc(C(=O)c2ccn3C(SCc23)c2cccnc2)c2ccc(Oc3ccc(F)cc3)cc12

InChI Key: InChIKey=WDFLVZOGBMHALR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Cavia porcellus)	BDBM50285993 (6-(4-Fluoro-phenoxy)-3-(3-pyridin-3-yl-1H-pyrrolo[...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccn3C(SCc23)c2cccnc2)c2ccc(Oc3ccc(F)cc3)cc12 Show InChI InChI=1S/C29H23FN4O3S/c1-32(2)29(36)34-16-24(22-10-9-21(14-25(22)34)37-20-7-5-19(30)6-8-20)27(35)23-11-13-33-26(23)17-38-28(33)18-4-3-12-31-15-18/h3-16,28H,17H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for antagonistic activity to displace [3H]-PAF from rabbit platelet membrane PAF receptors				Bioorg Med Chem Lett 5: 2903-2908 (1995) Article DOI: 10.1016/0960-894X(95)00509-R BindingDB Entry DOI: 10.7270/Q2WW7HN1
					More data for this Ligand-Target Pair