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BDBM50286013 (cis)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-1H-indole-3-carbonyl]-2-hydroxy-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-2-ium::(trans)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-1H-indole-3-carbonyl]-2-hydroxy-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-2-ium::CHEMBL538366

SMILES: CN(C)C(=O)n1cc(C(=O)c2ccn3[C@@H](c4cccnc4)S(=O)Cc23)c2ccc(cc12)-c1ccc(F)cc1

InChI Key: InChIKey=UNTMQSIAYRMPFW-GOGSRFGOSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286013   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PTAFR


(RAT)
BDBM50286013
PNG
((cis)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-p...)
Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccn3[C@@H](c4cccnc4)S(=O)Cc23)c2ccc(cc12)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C29H23FN4O3S/c1-32(2)29(36)34-16-24(22-10-7-19(14-25(22)34)18-5-8-21(30)9-6-18)27(35)23-11-13-33-26(23)17-38(37)28(33)20-4-3-12-31-15-20/h3-16,28H,17H2,1-2H3/t28-,38?/m1/s1
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
8.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor(PAF) by binding to PAF receptor


Bioorg Med Chem Lett 5: 2909-2912 (1995)


Article DOI: 10.1016/0960-894X(95)00510-Z
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(RAT)
BDBM50286013
PNG
((cis)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-p...)
Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccn3[C@@H](c4cccnc4)S(=O)Cc23)c2ccc(cc12)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C29H23FN4O3S/c1-32(2)29(36)34-16-24(22-10-7-19(14-25(22)34)18-5-8-21(30)9-6-18)27(35)23-11-13-33-26(23)17-38(37)28(33)20-4-3-12-31-15-20/h3-16,28H,17H2,1-2H3/t28-,38?/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
68n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor(PAF) by binding to PAF receptor


Bioorg Med Chem Lett 5: 2909-2912 (1995)


Article DOI: 10.1016/0960-894X(95)00510-Z
More data for this
Ligand-Target Pair