null

SMILES: COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1

InChI Key: InChIKey=DIWFHEYPDQRWTR-IRLVDXFISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) Show SMILES COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 |c:3,10,TLB:24:25:5:15.13.14,26:9:2:12.5.6,16:15:5:25.19.18,THB:4:5:25.19.18:15.13.14| Show InChI InChI=1S/C28H30N2O2/c1-25-17-26-11-12-28(25,32-3)24(29-23(25)18-7-5-4-6-8-18)27(26)13-14-30(2)22(26)15-19-9-10-20(31)16-21(19)27/h4-12,16,22,24,31H,13-15,17H2,1-3H3/t22?,24-,25-,26?,27?,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to displace [3H]-Cl-DPDPE from delta opioid receptor in hartley guinea pig brain membrane in the presence of 100 ...				Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) Show SMILES COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 |c:3,10,TLB:24:25:5:15.13.14,26:9:2:12.5.6,16:15:5:25.19.18,THB:4:5:25.19.18:15.13.14| Show InChI InChI=1S/C28H30N2O2/c1-25-17-26-11-12-28(25,32-3)24(29-23(25)18-7-5-4-6-8-18)27(26)13-14-30(2)22(26)15-19-9-10-20(31)16-21(19)27/h4-12,16,22,24,31H,13-15,17H2,1-3H3/t22?,24-,25-,26?,27?,28?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membrane				Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) Show SMILES COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 |c:3,10,TLB:24:25:5:15.13.14,26:9:2:12.5.6,16:15:5:25.19.18,THB:4:5:25.19.18:15.13.14| Show InChI InChI=1S/C28H30N2O2/c1-25-17-26-11-12-28(25,32-3)24(29-23(25)18-7-5-4-6-8-18)27(26)13-14-30(2)22(26)15-19-9-10-20(31)16-21(19)27/h4-12,16,22,24,31H,13-15,17H2,1-3H3/t22?,24-,25-,26?,27?,28?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to displace [3H]-U-69,593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 10...				Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) Show SMILES COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 |c:3,10,TLB:24:25:5:15.13.14,26:9:2:12.5.6,16:15:5:25.19.18,THB:4:5:25.19.18:15.13.14| Show InChI InChI=1S/C28H30N2O2/c1-25-17-26-11-12-28(25,32-3)24(29-23(25)18-7-5-4-6-8-18)27(26)13-14-30(2)22(26)15-19-9-10-20(31)16-21(19)27/h4-12,16,22,24,31H,13-15,17H2,1-3H3/t22?,24-,25-,26?,27?,28?/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to displace [3H]-DAMGO from mu opioid receptor in hartley guinea pig brain membrane in the presence of 100 nM of ...				Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT
					More data for this Ligand-Target Pair