null
SMILES: COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1
InChI Key: InChIKey=DIWFHEYPDQRWTR-IRLVDXFISA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to displace [3H]-Cl-DPDPE from delta opioid receptor in hartley guinea pig brain membrane in the presence of 100 ... | Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membrane | Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to displace [3H]-U-69,593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 10... | Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50286103 (CHEMBL102092 | Morphinan Cyclic Imine analogue) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to displace [3H]-DAMGO from mu opioid receptor in hartley guinea pig brain membrane in the presence of 100 nM of ... | Bioorg Med Chem Lett 5: 2969-2974 (1995) Article DOI: 10.1016/0960-894X(95)00522-1 BindingDB Entry DOI: 10.7270/Q24F1QQT | |||||||||||
More data for this Ligand-Target Pair |