BDBM50286162 CHEMBL105303::Dimethyl-carbamic acid (R)-3-(4-benzoyl-piperidin-1-yl)-3-oxo-2-(3-m-tolyl-ureido)-propyl ester

SMILES: CN(C)C(=O)OC[C@@H](NC(=O)Nc1cccc(C)c1)C(=O)N1CCC(CC1)C(=O)c1ccccc1

InChI Key: InChIKey=QXNYTXXTVJREMH-JOCHJYFZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50286162 (CHEMBL105303 | Dimethyl-carbamic acid (R)-3-(4-ben...) Show SMILES CN(C)C(=O)OC[C@@H](NC(=O)Nc1cccc(C)c1)C(=O)N1CCC(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C26H32N4O5/c1-18-8-7-11-21(16-18)27-25(33)28-22(17-35-26(34)29(2)3)24(32)30-14-12-20(13-15-30)23(31)19-9-5-4-6-10-19/h4-11,16,20,22H,12-15,17H2,1-3H3,(H2,27,28,33)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity towards binding of [125I]-Bolton-Hunter-CCK-8 to CCKB receptor in guinea pig cortical tissue				Bioorg Med Chem Lett 5: 3057-3062 (1995) Article DOI: 10.1016/0960-894X(95)00537-3 BindingDB Entry DOI: 10.7270/Q2BZ6604
					More data for this Ligand-Target Pair
Cholecystokinin A receptor (Cavia porcellus)	BDBM50286162 (CHEMBL105303 | Dimethyl-carbamic acid (R)-3-(4-ben...) Show SMILES CN(C)C(=O)OC[C@@H](NC(=O)Nc1cccc(C)c1)C(=O)N1CCC(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C26H32N4O5/c1-18-8-7-11-21(16-18)27-25(33)28-22(17-35-26(34)29(2)3)24(32)30-14-12-20(13-15-30)23(31)19-9-5-4-6-10-19/h4-11,16,20,22H,12-15,17H2,1-3H3,(H2,27,28,33)/t22-/m1/s1	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity towards binding of [125I]-Bolton-Hunter-CCK-8 to CCKA receptor in guinea pig pancreatic tissue				Bioorg Med Chem Lett 5: 3057-3062 (1995) Article DOI: 10.1016/0960-894X(95)00537-3 BindingDB Entry DOI: 10.7270/Q2BZ6604
					More data for this Ligand-Target Pair