BDBM50286239 CHEMBL315927::[(1S,4R,5R)-11-((S)-Isobutyl)-14-((R)-isopropyl)-8-naphthalen-1-ylmethyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid
SMILES: CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc2cccc3ccccc23)NC1=O)C(C)C
InChI Key: InChIKey=VIKVVYZEMQCXCA-BKVOUIBNSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50286239 (CHEMBL315927 | [(1S,4R,5R)-11-((S)-Isobutyl)-14-((...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 224 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity against ET A receptor | Bioorg Med Chem Lett 5: 253-258 (1995) Article DOI: 10.1016/0960-894X(95)00019-P BindingDB Entry DOI: 10.7270/Q2X067JB | |||||||||||
More data for this Ligand-Target Pair |