BDBM50286355 (R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-succinamide::CHEMBL324369

SMILES: CC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC

InChI Key: InChIKey=ZUZHAPXKYPLQLC-ABAIWWIYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50286355 ((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...) Show SMILES CC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC Show InChI InChI=1S/C18H24N4O4/c1-3-11(9-16(23)22-26)17(24)21-15(18(25)19-2)8-12-10-20-14-7-5-4-6-13(12)14/h4-7,10-11,15,20,26H,3,8-9H2,1-2H3,(H,19,25)(H,21,24)(H,22,23)/t11-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloproteinase-9				Bioorg Med Chem Lett 5: 349-352 (1995) Article DOI: 10.1016/0960-894X(95)00033-P BindingDB Entry DOI: 10.7270/Q2DR2VG9
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50286355 ((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...) Show SMILES CC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC Show InChI InChI=1S/C18H24N4O4/c1-3-11(9-16(23)22-26)17(24)21-15(18(25)19-2)8-12-10-20-14-7-5-4-6-13(12)14/h4-7,10-11,15,20,26H,3,8-9H2,1-2H3,(H,19,25)(H,21,24)(H,22,23)/t11-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human Matrix metalloproteinase-8				Bioorg Med Chem Lett 5: 349-352 (1995) Article DOI: 10.1016/0960-894X(95)00033-P BindingDB Entry DOI: 10.7270/Q2DR2VG9
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50286355 ((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...) Show SMILES CC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC Show InChI InChI=1S/C18H24N4O4/c1-3-11(9-16(23)22-26)17(24)21-15(18(25)19-2)8-12-10-20-14-7-5-4-6-13(12)14/h4-7,10-11,15,20,26H,3,8-9H2,1-2H3,(H,19,25)(H,21,24)(H,22,23)/t11-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human fibroblast collagenase, matrix metalloproteinase-1				Bioorg Med Chem Lett 5: 349-352 (1995) Article DOI: 10.1016/0960-894X(95)00033-P BindingDB Entry DOI: 10.7270/Q2DR2VG9
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50286355 ((R)-2-Ethyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...) Show SMILES CC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC Show InChI InChI=1S/C18H24N4O4/c1-3-11(9-16(23)22-26)17(24)21-15(18(25)19-2)8-12-10-20-14-7-5-4-6-13(12)14/h4-7,10-11,15,20,26H,3,8-9H2,1-2H3,(H,19,25)(H,21,24)(H,22,23)/t11-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3				Bioorg Med Chem Lett 5: 349-352 (1995) Article DOI: 10.1016/0960-894X(95)00033-P BindingDB Entry DOI: 10.7270/Q2DR2VG9
					More data for this Ligand-Target Pair