BDBM50286427 1-(2-Chloro-4-hydroxy-phenyl)-7-(2-fluoro-pyridin-4-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid amide::CHEMBL126718

SMILES: NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(ccc2c1=O)-c1ccnc(F)c1

InChI Key: InChIKey=POTQROHQFKCLJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50286427 (1-(2-Chloro-4-hydroxy-phenyl)-7-(2-fluoro-pyridin-...) Show SMILES NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(ccc2c1=O)-c1ccnc(F)c1 Show InChI InChI=1S/C21H13ClFN3O3/c22-16-9-13(27)2-4-17(16)26-10-15(21(24)29)20(28)14-3-1-11(7-18(14)26)12-5-6-25-19(23)8-12/h1-10,27H,(H2,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against human erythrocyte Calpain 1				Bioorg Med Chem Lett 5: 387-392 (1995) Article DOI: 10.1016/0960-894X(95)00041-Q BindingDB Entry DOI: 10.7270/Q21G0M6W
					More data for this Ligand-Target Pair