BDBM50286429 1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridazin-3-yl-1,4-dihydro-quinoline-3-carboxylic acid amide::CHEMBL337944

SMILES: NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(ccc2c1=O)-c1cccnn1

InChI Key: InChIKey=PWFLXMHXXMDHPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50286429 (1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridazin-3-...) Show SMILES NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(ccc2c1=O)-c1cccnn1 Show InChI InChI=1S/C20H13ClN4O3/c21-15-9-12(26)4-6-17(15)25-10-14(20(22)28)19(27)13-5-3-11(8-18(13)25)16-2-1-7-23-24-16/h1-10,26H,(H2,22,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against human erythrocyte Calpain 1				Bioorg Med Chem Lett 5: 387-392 (1995) Article DOI: 10.1016/0960-894X(95)00041-Q BindingDB Entry DOI: 10.7270/Q21G0M6W
					More data for this Ligand-Target Pair