BDBM50286563 6-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-en-1-ynyl]-nicotinic acid::CHEMBL150691

SMILES: CC1=C(\C=C\C#Cc2ccc(cn2)C(O)=O)C(C)(C)CCC1

InChI Key: InChIKey=DSQMLDQMOIVLSY-WEVVVXLNSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50286563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid receptor (Homo sapiens (Human))	BDBM50286563 (6-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-e...) Show SMILES CC1=C(\C=C\C#Cc2ccc(cn2)C(O)=O)C(C)(C)CCC1 |c:1| Show InChI InChI=1S/C19H21NO2/c1-14-7-6-12-19(2,3)17(14)9-5-4-8-16-11-10-15(13-20-16)18(21)22/h5,9-11,13H,6-7,12H2,1-3H3,(H,21,22)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	>15	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR gamma				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50286563 (6-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-e...) Show SMILES CC1=C(\C=C\C#Cc2ccc(cn2)C(O)=O)C(C)(C)CCC1 |c:1| Show InChI InChI=1S/C19H21NO2/c1-14-7-6-12-19(2,3)17(14)9-5-4-8-16-11-10-15(13-20-16)18(21)22/h5,9-11,13H,6-7,12H2,1-3H3,(H,21,22)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR alpha; not active				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50286563 (6-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-e...) Show SMILES CC1=C(\C=C\C#Cc2ccc(cn2)C(O)=O)C(C)(C)CCC1 |c:1| Show InChI InChI=1S/C19H21NO2/c1-14-7-6-12-19(2,3)17(14)9-5-4-8-16-11-10-15(13-20-16)18(21)22/h5,9-11,13H,6-7,12H2,1-3H3,(H,21,22)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	>5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR beta				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair