BDBM50286591 (R)-5-{(S)-2-[((R)-sec-Butyl)-((S)-sec-butyl)-amino]-1-hydroxy-ethyl}-1-(2-chloro-benzyl)-pyrrolidin-2-one::CHEMBL346354
SMILES: CC[C@H](C)N(C[C@H](O)[C@H]1CCC(=O)N1Cc1ccccc1Cl)[C@H](C)CC
InChI Key: InChIKey=YNGZJSALRCLELM-GJJHYRHESA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50286591 ((R)-5-{(S)-2-[((R)-sec-Butyl)-((S)-sec-butyl)-amin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 198 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenate | Bioorg Med Chem Lett 5: 589-592 (1995) Article DOI: 10.1016/0960-894X(95)00077-7 BindingDB Entry DOI: 10.7270/Q2M908PK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50286591 ((R)-5-{(S)-2-[((R)-sec-Butyl)-((S)-sec-butyl)-amin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenate | Bioorg Med Chem Lett 5: 589-592 (1995) Article DOI: 10.1016/0960-894X(95)00077-7 BindingDB Entry DOI: 10.7270/Q2M908PK | |||||||||||
More data for this Ligand-Target Pair |