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SMILES: CC(C)(C)NC(=O)c1ccccc1C[C@@H](O)[C@H](CSc1ccc2ccccc2c1)NC(=O)c1cccc2ncccc12

InChI Key: InChIKey=PWUBUZXXOHMQNZ-AJQTZOPKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286711   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM50286711
PNG
(CHEMBL354231 | Quinoline-5-carboxylic acid [(1R,2R...)
Show SMILES CC(C)(C)NC(=O)c1ccccc1C[C@@H](O)[C@H](CSc1ccc2ccccc2c1)NC(=O)c1cccc2ncccc12
Show InChI InChI=1S/C35H35N3O3S/c1-35(2,3)38-34(41)27-13-7-6-12-25(27)21-32(39)31(22-42-26-18-17-23-10-4-5-11-24(23)20-26)37-33(40)29-14-8-16-30-28(29)15-9-19-36-30/h4-20,31-32,39H,21-22H2,1-3H3,(H,37,40)(H,38,41)/t31-,32+/m0/s1
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Article
 113n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity HIV-1 protease enzyme

Bioorg Med Chem Lett 5: 727-732 (1995)


Article DOI: 10.1016/0960-894X(95)00103-Z
BindingDB Entry DOI: 10.7270/Q29S1R0T
More data for this
Ligand-Target Pair