BDBM50286742 4-[7-(4-Fluoro-phenyl)-spiro[3.4]oct-6-en-6-yl]-benzenesulfonamide::CHEMBL171335
SMILES: NS(=O)(=O)c1ccc(cc1)C1=C(CC2(CCC2)C1)c1ccc(F)cc1
InChI Key: InChIKey=DFJVUELGIACRGE-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase (Homo sapiens (Human)) | BDBM50286742 (4-[7-(4-Fluoro-phenyl)-spiro[3.4]oct-6-en-6-yl]-be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated in vitro for the inhibitory activity against inducible form of human recombinant Prostaglandin G/H synthase 1 | Bioorg Med Chem Lett 5: 867-872 (1995) Article DOI: 10.1016/0960-894X(95)00131-C BindingDB Entry DOI: 10.7270/Q2P26Z3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50286742 (4-[7-(4-Fluoro-phenyl)-spiro[3.4]oct-6-en-6-yl]-be...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated in vitro for the inhibitory activity against constitutive form of human recombinant Prostaglandin G/H synthase 1 | Bioorg Med Chem Lett 5: 867-872 (1995) Article DOI: 10.1016/0960-894X(95)00131-C BindingDB Entry DOI: 10.7270/Q2P26Z3Q | |||||||||||
More data for this Ligand-Target Pair |