BDBM50287152 2-[1,2-Bis-(2-fluoro-phenyl)-ethyl]-1H-indole-5-carboxamidine::CHEMBL284885

SMILES: NC(=N)c1ccc2[nH]c(cc2c1)C(Cc1ccccc1F)c1ccccc1F

InChI Key: InChIKey=ILLFKAVVQANXDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50287152 (2-[1,2-Bis-(2-fluoro-phenyl)-ethyl]-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)C(Cc1ccccc1F)c1ccccc1F Show InChI InChI=1S/C23H19F2N3/c24-19-7-3-1-5-14(19)12-18(17-6-2-4-8-20(17)25)22-13-16-11-15(23(26)27)9-10-21(16)28-22/h1-11,13,18,28H,12H2,(H3,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of human alpha-thrombin catalytic activity.				Bioorg Med Chem Lett 6: 1339-1344 (1996) Article DOI: 10.1016/0960-894X(96)00229-6 BindingDB Entry DOI: 10.7270/Q2TM7B2Z
					More data for this Ligand-Target Pair