BDBM50287159 2-(3-Phenoxy-benzyl)-1H-indole-5-carboxamidine::CHEMBL27805
SMILES: NC(=N)c1ccc2[nH]c(Cc3cccc(Oc4ccccc4)c3)cc2c1
InChI Key: InChIKey=HICLOEGENKPBRC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50287159 (2-(3-Phenoxy-benzyl)-1H-indole-5-carboxamidine | C...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of human alpha-thrombin catalytic activity. | Bioorg Med Chem Lett 6: 1339-1344 (1996) Article DOI: 10.1016/0960-894X(96)00229-6 BindingDB Entry DOI: 10.7270/Q2TM7B2Z | |||||||||||
More data for this Ligand-Target Pair |