BDBM50287173 4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide::CHEMBL416939

SMILES: COc1c(cc(Cl)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1

InChI Key: InChIKey=ARZYDJJAHRASCM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287173 (4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [...) Show SMILES COc1c(cc(Cl)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C24H26ClN3O2/c1-30-23-20-10-6-5-9-19(20)22(25)17-21(23)24(29)26-11-12-27-13-15-28(16-14-27)18-7-3-2-4-8-18/h2-10,17H,11-16H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki				J Med Chem 40: 833-40 (1997) Article DOI: 10.1021/jm9605952 BindingDB Entry DOI: 10.7270/Q23J3F5T
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287173 (4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [...) Show SMILES COc1c(cc(Cl)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C24H26ClN3O2/c1-30-23-20-10-6-5-9-19(20)22(25)17-21(23)24(29)26-11-12-27-13-15-28(16-14-27)18-7-3-2-4-8-18/h2-10,17H,11-16H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50287173 (4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [...) Show SMILES COc1c(cc(Cl)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C24H26ClN3O2/c1-30-23-20-10-6-5-9-19(20)22(25)17-21(23)24(29)26-11-12-27-13-15-28(16-14-27)18-7-3-2-4-8-18/h2-10,17H,11-16H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D2 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair