BDBM50287176 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL30206

SMILES: COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1Cl

InChI Key: InChIKey=OSSGYBFCUFQSTI-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287176 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C24H25BrClN3O2/c1-31-23-18-7-3-2-6-17(18)20(25)16-19(23)24(30)27-10-11-28-12-14-29(15-13-28)22-9-5-4-8-21(22)26/h2-9,16H,10-15H2,1H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287176 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C24H25BrClN3O2/c1-31-23-18-7-3-2-6-17(18)20(25)16-19(23)24(30)27-10-11-28-12-14-29(15-13-28)22-9-5-4-8-21(22)26/h2-9,16H,10-15H2,1H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki				J Med Chem 40: 833-40 (1997) Article DOI: 10.1021/jm9605952 BindingDB Entry DOI: 10.7270/Q23J3F5T
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50287176 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C24H25BrClN3O2/c1-31-23-18-7-3-2-6-17(18)20(25)16-19(23)24(30)27-10-11-28-12-14-29(15-13-28)22-9-5-4-8-21(22)26/h2-9,16H,10-15H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	517	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D2 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287176 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1Cl Show InChI InChI=1S/C24H25BrClN3O2/c1-31-23-18-7-3-2-6-17(18)20(25)16-19(23)24(30)27-10-11-28-12-14-29(15-13-28)22-9-5-4-8-21(22)26/h2-9,16H,10-15H2,1H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair