BDBM50287319 CHEMBL38949::[3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(6-chloro-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-prop-(E)-ylideneaminooxy]-acetic acid

SMILES: CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3cccc(Cl)n3)cc12

InChI Key: InChIKey=GZWGPAWFRAKIMD-JEPNHJGPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-Lipoxygenase/5-lipoxygenase activating protein (Homo sapiens (Human))	BDBM50287319 (CHEMBL38949 | [3-[3-tert-Butylsulfanyl-1-(4-chloro...) Show SMILES CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3cccc(Cl)n3)cc12 Show InChI InChI=1S/C32H35Cl2N3O4S/c1-31(2,3)42-30-25-15-24(40-18-23-7-6-8-28(34)36-23)13-14-26(25)37(17-21-9-11-22(33)12-10-21)27(30)16-32(4,5)20-35-41-19-29(38)39/h6-15,20H,16-19H2,1-5H3,(H,38,39)/b35-20+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassay				Bioorg Med Chem Lett 6: 1547-1552 (1996) Article DOI: 10.1016/S0960-894X(96)00271-5 BindingDB Entry DOI: 10.7270/Q2DF6R6W
					More data for this Ligand-Target Pair
5-Lipoxygenase/5-lipoxygenase activating protein (Homo sapiens (Human))	BDBM50287319 (CHEMBL38949 | [3-[3-tert-Butylsulfanyl-1-(4-chloro...) Show SMILES CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3cccc(Cl)n3)cc12 Show InChI InChI=1S/C32H35Cl2N3O4S/c1-31(2,3)42-30-25-15-24(40-18-23-7-6-8-28(34)36-23)13-14-26(25)37(17-21-9-11-22(33)12-10-21)27(30)16-32(4,5)20-35-41-19-29(38)39/h6-15,20H,16-19H2,1-5H3,(H,38,39)/b35-20+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassay				Bioorg Med Chem Lett 6: 1547-1552 (1996) Article DOI: 10.1016/S0960-894X(96)00271-5 BindingDB Entry DOI: 10.7270/Q2DF6R6W
					More data for this Ligand-Target Pair