BDBM50287474 3,3-Difluoro-1-((2S,4aS,8aS)-4a-methyl-decahydro-naphthalen-2-yl)-pentadecan-2-one::CHEMBL288982

SMILES: CCCCCCCCCCCCC(F)(F)C(=O)C[C@H]1CC[C@]2(C)CCCC[C@H]2C1

InChI Key: InChIKey=LNMDIGIMSSIYGF-LSQMVHIFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid lipase/cholesteryl ester hydrolase (Homo sapiens (Human))	BDBM50287474 (3,3-Difluoro-1-((2S,4aS,8aS)-4a-methyl-decahydro-n...) Show SMILES CCCCCCCCCCCCC(F)(F)C(=O)C[C@H]1CC[C@]2(C)CCCC[C@H]2C1 Show InChI InChI=1S/C26H46F2O/c1-3-4-5-6-7-8-9-10-11-13-18-26(27,28)24(29)21-22-16-19-25(2)17-14-12-15-23(25)20-22/h22-23H,3-21H2,1-2H3/t22-,23-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ancreatic cholesterol esterase using using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substrates				Bioorg Med Chem Lett 6: 1673-1676 (1996) Article DOI: 10.1016/0960-894X(96)00290-9 BindingDB Entry DOI: 10.7270/Q2H70FSC
					More data for this Ligand-Target Pair