BDBM50287489 7-Hydroxycarbamoylmethyl-bicyclo[4.2.0]octa-1(6),2,4-triene-7-carboxylic acid [(S)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-amide::CHEMBL295257

SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C1(CC(=O)NO)Cc2ccccc12

InChI Key: InChIKey=GUSOLUHJMMBUHD-HXBUSHRASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50287489 (7-Hydroxycarbamoylmethyl-bicyclo[4.2.0]octa-1(6),2...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C1(CC(=O)NO)Cc2ccccc12 Show InChI InChI=1S/C22H25N3O5/c1-23-20(27)18(11-14-7-9-16(30-2)10-8-14)24-21(28)22(13-19(26)25-29)12-15-5-3-4-6-17(15)22/h3-10,18,29H,11-13H2,1-2H3,(H,23,27)(H,24,28)(H,25,26)/t18-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Matrix Metallo Proteinase-1(MMP-1)				Bioorg Med Chem Lett 6: 1719-1724 (1996) Article DOI: 10.1016/0960-894X(96)00303-4 BindingDB Entry DOI: 10.7270/Q23X86K0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50287489 (7-Hydroxycarbamoylmethyl-bicyclo[4.2.0]octa-1(6),2...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C1(CC(=O)NO)Cc2ccccc12 Show InChI InChI=1S/C22H25N3O5/c1-23-20(27)18(11-14-7-9-16(30-2)10-8-14)24-21(28)22(13-19(26)25-29)12-15-5-3-4-6-17(15)22/h3-10,18,29H,11-13H2,1-2H3,(H,23,27)(H,24,28)(H,25,26)/t18-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Matrix Metallo Proteinase-1(MMP-1)				Bioorg Med Chem Lett 6: 1719-1724 (1996) Article DOI: 10.1016/0960-894X(96)00303-4 BindingDB Entry DOI: 10.7270/Q23X86K0
					More data for this Ligand-Target Pair