BDBM50287493 CHEMBL296142::N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-2-methyl-succinamide

SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(C)(CC(C)C)CC(=O)NO

InChI Key: InChIKey=OHSLOLSYLUBGHH-DJZRFWRSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50287493 (CHEMBL296142 | N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(C)(CC(C)C)CC(=O)NO Show InChI InChI=1S/C20H31N3O5/c1-13(2)11-20(3,12-17(24)23-27)19(26)22-16(18(25)21-4)10-14-6-8-15(28-5)9-7-14/h6-9,13,16,27H,10-12H2,1-5H3,(H,21,25)(H,22,26)(H,23,24)/t16-,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Matrix Metallo Proteinase-1(MMP-1)				Bioorg Med Chem Lett 6: 1719-1724 (1996) Article DOI: 10.1016/0960-894X(96)00303-4 BindingDB Entry DOI: 10.7270/Q23X86K0
					More data for this Ligand-Target Pair