BDBM50287527 6-(2-Isopropyl-benzenesulfonyl)-5-nitro-quinolin-8-ylamine::CHEMBL422942::PD-160170

SMILES: CC(C)c1ccccc1S(=O)(=O)c1cc(N)c2ncccc2c1[N+]([O-])=O

InChI Key: InChIKey=YUVNGBZROXQYQH-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50287527 (6-(2-Isopropyl-benzenesulfonyl)-5-nitro-quinolin-8...) Show SMILES CC(C)c1ccccc1S(=O)(=O)c1cc(N)c2ncccc2c1[N+]([O-])=O Show InChI InChI=1S/C18H17N3O4S/c1-11(2)12-6-3-4-8-15(12)26(24,25)16-10-14(19)17-13(7-5-9-20-17)18(16)21(22)23/h3-11H,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuropeptide Y1 (NPY1) receptor from SK-N-MC membranes using [125I]-PYY as radioligand				Bioorg Med Chem Lett 6: 1809-1814 (1996) Article DOI: 10.1016/0960-894X(96)00319-8 BindingDB Entry DOI: 10.7270/Q2M045FM
					More data for this Ligand-Target Pair
NPY2R (RAT)	BDBM50287527 (6-(2-Isopropyl-benzenesulfonyl)-5-nitro-quinolin-8...) Show SMILES CC(C)c1ccccc1S(=O)(=O)c1cc(N)c2ncccc2c1[N+]([O-])=O Show InChI InChI=1S/C18H17N3O4S/c1-11(2)12-6-3-4-8-15(12)26(24,25)16-10-14(19)17-13(7-5-9-20-17)18(16)21(22)23/h3-11H,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuropeptide Y2 (NPY2) receptor from rat hippocampi.				Bioorg Med Chem Lett 6: 1809-1814 (1996) Article DOI: 10.1016/0960-894X(96)00319-8 BindingDB Entry DOI: 10.7270/Q2M045FM
					More data for this Ligand-Target Pair