BDBM50287690 7-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-heptanoic acid::CHEMBL65610
SMILES: OC(=O)CCCCCCNC(=O)C1(CS)CCc2ccccc2C1
InChI Key: InChIKey=DYGXRRYDCDLZTH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50287690 (7-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of neutral endopeptidase(NEP). | Bioorg Med Chem Lett 6: 2053-2058 (1996) Article DOI: 10.1016/0960-894X(96)00367-8 BindingDB Entry DOI: 10.7270/Q29G5MSW | |||||||||||
More data for this Ligand-Target Pair |