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BDBM50287814 (S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidine::CHEMBL74249

SMILES: CN1CCC[C@H]1COc1cccc(F)c1

InChI Key: InChIKey=YMSPBBGEZQILFC-NSHDSACASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287814   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287814
PNG
((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Show SMILES CN1CCC[C@H]1COc1cccc(F)c1
Show InChI InChI=1S/C12H16FNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)


Article DOI: 10.1016/0960-894X(96)00416-7
BindingDB Entry DOI: 10.7270/Q2C82999
More data for this
Ligand-Target Pair