BDBM50287948 CHEMBL64886::[(2S,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3,4-b]quinolin-1-yl)-4-(2-nitro-benzenesulfonyl)-morpholin-2-yl]-methanol

SMILES: COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO)O1)Sc1ccccc1[N+]([O-])=O

InChI Key: InChIKey=WXWCUWNSDGKFFF-MGPUTAFESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase HRas (Homo sapiens (Human))	BDBM50287948 (CHEMBL64886 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-met...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO)O1)Sc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C23H22ClN5O5S/c1-13-21-22(24)16-9-14(33-2)7-8-17(16)25-23(21)28(26-13)20-11-27(10-15(12-30)34-20)35-19-6-4-3-5-18(19)29(31)32/h3-9,15,20,30H,10-12H2,1-2H3/t15-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair