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SMILES: CSCO[C@@]1(C)CO[C@@](C)(CC(=O)OC[C@H]2O[C@H](C[C@@H]2O[Si](C)(C)C(C)(C)C)n2cc(C)c(=O)[nH]c2=O)C1

InChI Key: InChIKey=HFDYRWSLZWTVOV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288070   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50288070
PNG
((2,4-Dimethyl-4-methylsulfanylmethoxy-tetrahydro-f...)
Show SMILES CSCO[C@@]1(C)CO[C@@](C)(CC(=O)OC[C@H]2O[C@H](C[C@@H]2O[Si](C)(C)C(C)(C)C)n2cc(C)c(=O)[nH]c2=O)C1 |r|
Show InChI InChI=1S/C26H44N2O8SSi/c1-17-12-28(23(31)27-22(17)30)20-10-18(36-38(8,9)24(2,3)4)19(35-20)13-32-21(29)11-25(5)14-26(6,15-33-25)34-16-37-7/h12,18-20H,10-11,13-16H2,1-9H3,(H,27,30,31)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase

Bioorg Med Chem Lett 6: 2411-2416 (1996)


Article DOI: 10.1016/0960-894X(96)00443-X
BindingDB Entry DOI: 10.7270/Q2TB16VK
More data for this
Ligand-Target Pair