BDBM50288236 2-[3-(2,6-Diisopropyl-phenyl)-ureido]-N-(2,2-dimethyl-[1,3]dioxan-5-yl)-3-(1H-indol-3-yl)-2-methyl-propionamide::CHEMBL92274

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NC1COC(C)(C)OC1

InChI Key: InChIKey=COZVPGGEDBOYRG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50288236 (2-[3-(2,6-Diisopropyl-phenyl)-ureido]-N-(2,2-dimet...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NC1COC(C)(C)OC1 Show InChI InChI=1S/C31H42N4O4/c1-19(2)23-12-10-13-24(20(3)4)27(23)34-29(37)35-31(7,15-21-16-32-26-14-9-8-11-25(21)26)28(36)33-22-17-38-30(5,6)39-18-22/h8-14,16,19-20,22,32H,15,17-18H2,1-7H3,(H,33,36)(H2,34,35,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cells				Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD
					More data for this Ligand-Target Pair
GRPR (Homo sapiens (Human))	BDBM50288236 (2-[3-(2,6-Diisopropyl-phenyl)-ureido]-N-(2,2-dimet...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NC1COC(C)(C)OC1 Show InChI InChI=1S/C31H42N4O4/c1-19(2)23-12-10-13-24(20(3)4)27(23)34-29(37)35-31(7,15-21-16-32-26-14-9-8-11-25(21)26)28(36)33-22-17-38-30(5,6)39-18-22/h8-14,16,19-20,22,32H,15,17-18H2,1-7H3,(H,33,36)(H2,34,35,37)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human GRP(gastrin releasing peptide) receptors stably expressed in CHO cells				Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD
					More data for this Ligand-Target Pair