BDBM50288254 2-ammonio-4-oxo-4-phenyl-(2S)-butanoate::CHEMBL315803
SMILES: [NH3+][C@@H](CC(=O)c1ccccc1)C([O-])=O
InChI Key: InChIKey=QXRCVKLRAOSZCP-QMMMGPOBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynureninase (Homo sapiens (Human)) | BDBM50288254 (2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | Article | 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence | Bioorg Med Chem Lett 6: 2643-2646 (1996) Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PA/PB1 (Hepatitis C virus) | BDBM50288254 (2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of cap 1 ALMV primed Influenza transcriptase | Antimicrob Agents Chemother 38: 2827-37 (1995) BindingDB Entry DOI: 10.7270/Q25H7HBP | |||||||||||
More data for this Ligand-Target Pair |