BDBM50288595 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid 1-butyl-piperidin-4-ylmethyl ester::CHEMBL315071

SMILES: CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3CCOc23)CC1

InChI Key: InChIKey=IXXTXCSTYLTTPX-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (RAT)	BDBM50288595 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3CCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O3/c1-2-3-7-22-8-4-13(5-9-22)12-25-19(23)15-11-16(20)17(21)14-6-10-24-18(14)15/h11,13H,2-10,12,21H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.				Bioorg Med Chem Lett 6: 263-266 (1996) Article DOI: 10.1016/0960-894X(96)00002-9 BindingDB Entry DOI: 10.7270/Q2MC90JK
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50288595 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3CCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O3/c1-2-3-7-22-8-4-13(5-9-22)12-25-19(23)15-11-16(20)17(21)14-6-10-24-18(14)15/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.				Bioorg Med Chem Lett 6: 263-266 (1996) Article DOI: 10.1016/0960-894X(96)00002-9 BindingDB Entry DOI: 10.7270/Q2MC90JK
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50288595 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3CCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O3/c1-2-3-7-22-8-4-13(5-9-22)12-25-19(23)15-11-16(20)17(21)14-6-10-24-18(14)15/h11,13H,2-10,12,21H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.				Bioorg Med Chem Lett 6: 263-266 (1996) Article DOI: 10.1016/0960-894X(96)00002-9 BindingDB Entry DOI: 10.7270/Q2MC90JK
					More data for this Ligand-Target Pair