BDBM50288610 Alpha-ketocarbonyl derivative::CHEMBL98937
SMILES: CC(C)CC(NC(=O)C(CCCN=C(N)N[N+]([O-])=O)NC(=O)C(CCCCCCCCC#N)C1CCCC1)C(=O)CCl
InChI Key: InChIKey=SGOLVTXDPRFQNJ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chymotrypsin-like protease CTRL-1 (Homo sapiens (Human)) | BDBM50288610 (Alpha-ketocarbonyl derivative | CHEMBL98937) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for thromboxane TXA2 synthase inhibitory activity using human platelet | Bioorg Med Chem Lett 6: 287-290 (1996) Article DOI: 10.1016/0960-894X(96)00014-5 BindingDB Entry DOI: 10.7270/Q2JQ1112 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymotrypsin-like protease CTRL-1 (Homo sapiens (Human)) | BDBM50288610 (Alpha-ketocarbonyl derivative | CHEMBL98937) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brain | Bioorg Med Chem Lett 6: 287-290 (1996) Article DOI: 10.1016/0960-894X(96)00014-5 BindingDB Entry DOI: 10.7270/Q2JQ1112 | |||||||||||
More data for this Ligand-Target Pair |