BDBM50288958 2-Biphenyl-4-yl-N-((R)-1-mercaptomethyl-2-pyridin-3-yl-ethyl)-acetamide::CHEMBL156879

SMILES: SC[C@@H](Cc1cccnc1)NC(=O)Cc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=JIEYFJMFLWBNBY-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288958   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50288958 (2-Biphenyl-4-yl-N-((R)-1-mercaptomethyl-2-pyridin-...) Show SMILES SC[C@@H](Cc1cccnc1)NC(=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H22N2OS/c25-22(24-21(16-26)13-18-5-4-12-23-15-18)14-17-8-10-20(11-9-17)19-6-2-1-3-7-19/h1-12,15,21,26H,13-14,16H2,(H,24,25)/t21-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cells				Bioorg Med Chem Lett 6: 619-624 (1996) Article DOI: 10.1016/0960-894X(96)00091-1 BindingDB Entry DOI: 10.7270/Q26973K3
					More data for this Ligand-Target Pair