BDBM50288960 CHEMBL156638::N-[(R)-2-(1H-Indol-3-yl)-1-mercaptomethyl-ethyl]-2-phenyl-acetamide

SMILES: SC[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1ccccc1

InChI Key: InChIKey=CLKHZXGEQOXPQG-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50288960 (CHEMBL156638 | N-[(R)-2-(1H-Indol-3-yl)-1-mercapto...) Show SMILES SC[C@@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C19H20N2OS/c22-19(10-14-6-2-1-3-7-14)21-16(13-23)11-15-12-20-18-9-5-4-8-17(15)18/h1-9,12,16,20,23H,10-11,13H2,(H,21,22)/t16-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of Endothelin-converting enzyme 1 partially purified from porcine primary aortic endothelial cells				Bioorg Med Chem Lett 6: 619-624 (1996) Article DOI: 10.1016/0960-894X(96)00091-1 BindingDB Entry DOI: 10.7270/Q26973K3
					More data for this Ligand-Target Pair