new BindingDB logo
myBDB logout

BDBM50288999 2-(2-Iodo-phenyl)-7-methyl-benzo[d][1,3]oxazin-4-one::CHEMBL345362

SMILES: Cc1ccc2c(c1)nc(oc2=O)-c1ccccc1I

InChI Key: InChIKey=REDGKVBOUYXRLD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288999   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement C1r


(Homo sapiens (Human))
BDBM50288999
PNG
(2-(2-Iodo-phenyl)-7-methyl-benzo[d][1,3]oxazin-4-o...)
Show SMILES Cc1ccc2c(c1)nc(oc2=O)-c1ccccc1I
Show InChI InChI=1S/C15H10INO2/c1-9-6-7-11-13(8-9)17-14(19-15(11)18)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>6.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair
Complement C1r subcomponent


(Homo sapiens (Human))
BDBM50288999
PNG
(2-(2-Iodo-phenyl)-7-methyl-benzo[d][1,3]oxazin-4-o...)
Show SMILES Cc1ccc2c(c1)nc(oc2=O)-c1ccccc1I
Show InChI InChI=1S/C15H10INO2/c1-9-6-7-11-13(8-9)17-14(19-15(11)18)10-4-2-3-5-12(10)16/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>6.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against C1r serine protease


Bioorg Med Chem Lett 6: 679-682 (1996)


Article DOI: 10.1016/0960-894X(96)00094-7
BindingDB Entry DOI: 10.7270/Q2P84BVF
More data for this
Ligand-Target Pair