BDBM50289141 5-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole::CHEMBL354352
SMILES: Fc1ccc2[nH]cc(\C=C\c3ccncc3)c2c1
InChI Key: InChIKey=RXOULJUHAPQWKF-OWOJBTEDSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptophan 2,3-dioxygenase (Rattus norvegicus) | BDBM50289141 (5-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liver | Bioorg Med Chem Lett 6: 857-860 (1996) Article DOI: 10.1016/0960-894X(96)00124-2 BindingDB Entry DOI: 10.7270/Q2833S17 | |||||||||||
More data for this Ligand-Target Pair |