BDBM50289194 (S)-2-[(S)-4-((R)-2-Mercapto-3-phenyl-propionylamino)-3-oxo-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-4-methyl-pentanoic acid::CHEMBL366495::MDL-100407
SMILES: CC(C)C[C@H](N1Cc2ccccc2C[C@H](NC(=O)[C@H](S)Cc2ccccc2)C1=O)C(O)=O
InChI Key: InChIKey=MVSZLSBZJCTXKA-FDFHNCONSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50289194 ((S)-2-[(S)-4-((R)-2-Mercapto-3-phenyl-propionylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of neutral endopeptidase (NEP). | Bioorg Med Chem Lett 6: 957-962 (1996) Article DOI: 10.1016/0960-894X(96)00149-7 BindingDB Entry DOI: 10.7270/Q2BV7GMV | |||||||||||
More data for this Ligand-Target Pair |