null

SMILES: CS(=O)(=O)c1ccc(cc1)-c1sc2ncnn2c1-c1ccc(F)cc1

InChI Key: InChIKey=YUYGIQKCRIEWAR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50289316 (6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2ncnn2c1-c1ccc(F)cc1 Show InChI InChI=1S/C17H12FN3O2S2/c1-25(22,23)14-8-4-12(5-9-14)16-15(11-2-6-13(18)7-3-11)21-17(24-16)19-10-20-21/h2-10H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289316 (6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2ncnn2c1-c1ccc(F)cc1 Show InChI InChI=1S/C17H12FN3O2S2/c1-25(22,23)14-8-4-12(5-9-14)16-15(11-2-6-13(18)7-3-11)21-17(24-16)19-10-20-21/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.63E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of COX2 (unknown origin) expressed in CHO cells				Citation and Details Article DOI: 10.1007/s00044-004-0039-1 BindingDB Entry DOI: 10.7270/Q2280BHV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289316 (6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2ncnn2c1-c1ccc(F)cc1 Show InChI InChI=1S/C17H12FN3O2S2/c1-25(22,23)14-8-4-12(5-9-14)16-15(11-2-6-13(18)7-3-11)21-17(24-16)19-10-20-21/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair