null

SMILES: CS(=O)(=O)c1ccc(cc1)-c1c(sc2ncnn12)-c1ccccc1

InChI Key: InChIKey=BPMWHRGUWKLDJO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50289325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50289325 (6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(sc2ncnn12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O2S2/c1-24(21,22)14-9-7-12(8-10-14)15-16(13-5-3-2-4-6-13)23-17-18-11-19-20(15)17/h2-11H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289325 (6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(sc2ncnn12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O2S2/c1-24(21,22)14-9-7-12(8-10-14)15-16(13-5-3-2-4-6-13)23-17-18-11-19-20(15)17/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.24E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of COX2 (unknown origin) expressed in CHO cells				Citation and Details Article DOI: 10.1007/s00044-004-0039-1 BindingDB Entry DOI: 10.7270/Q2280BHV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289325 (6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(sc2ncnn12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O2S2/c1-24(21,22)14-9-7-12(8-10-14)15-16(13-5-3-2-4-6-13)23-17-18-11-19-20(15)17/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289325 (6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(sc2ncnn12)-c1ccccc1 Show InChI InChI=1S/C17H13N3O2S2/c1-24(21,22)14-9-7-12(8-10-14)15-16(13-5-3-2-4-6-13)23-17-18-11-19-20(15)17/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair