null

SMILES: CCc1nc2sc(c(-c3ccccc3)n2n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=NURGVZYLZIHTFO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50289332 (2-Ethyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-thia...) Show SMILES CCc1nc2sc(c(-c3ccccc3)n2n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H17N3O2S2/c1-3-16-20-19-22(21-16)17(13-7-5-4-6-8-13)18(25-19)14-9-11-15(12-10-14)26(2,23)24/h4-12H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289332 (2-Ethyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-thia...) Show SMILES CCc1nc2sc(c(-c3ccccc3)n2n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H17N3O2S2/c1-3-16-20-19-22(21-16)17(13-7-5-4-6-8-13)18(25-19)14-9-11-15(12-10-14)26(2,23)24/h4-12H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.51E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of COX2 (unknown origin) expressed in CHO cells				Citation and Details Article DOI: 10.1007/s00044-004-0039-1 BindingDB Entry DOI: 10.7270/Q2280BHV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289332 (2-Ethyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-thia...) Show SMILES CCc1nc2sc(c(-c3ccccc3)n2n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H17N3O2S2/c1-3-16-20-19-22(21-16)17(13-7-5-4-6-8-13)18(25-19)14-9-11-15(12-10-14)26(2,23)24/h4-12H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair