BDBM50289448 1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol::CHEMBL32402
SMILES: OC(COc1ccccc1)CN1CCC(CC1)Oc1ccccc1
InChI Key: InChIKey=AXPMHZJZVFNEBY-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50289448 (1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement. | Bioorg Med Chem Lett 7: 1377-1380 (1997) Article DOI: 10.1016/S0960-894X(97)00233-3 BindingDB Entry DOI: 10.7270/Q2WQ03SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50289448 (1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 537 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against cloned human D3 receptor transfected in CHO-K1 cells using [3H]- spiperone as radioligand. | Bioorg Med Chem Lett 7: 1377-1380 (1997) Article DOI: 10.1016/S0960-894X(97)00233-3 BindingDB Entry DOI: 10.7270/Q2WQ03SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50289448 (1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 911 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against cloned human D2 receptor transfected in CHO-K1 cells using [3H]- spiperone as radioligand. | Bioorg Med Chem Lett 7: 1377-1380 (1997) Article DOI: 10.1016/S0960-894X(97)00233-3 BindingDB Entry DOI: 10.7270/Q2WQ03SG | |||||||||||
More data for this Ligand-Target Pair |