BDBM50289567 2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetamide::CHEMBL38569

SMILES: C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1

InChI Key: InChIKey=MDPGYFIGIJWUFG-ACJLOTCBSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50289567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50289567 (2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...) Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells				Bioorg Med Chem Lett 7: 1583-1588 (1997) Article DOI: 10.1016/S0960-894X(97)00266-7 BindingDB Entry DOI: 10.7270/Q24749VQ
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50289567 (2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...) Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells				Bioorg Med Chem Lett 7: 1583-1588 (1997) Article DOI: 10.1016/S0960-894X(97)00266-7 BindingDB Entry DOI: 10.7270/Q24749VQ
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50289567 (2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...) Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells				Bioorg Med Chem Lett 7: 1583-1588 (1997) Article DOI: 10.1016/S0960-894X(97)00266-7 BindingDB Entry DOI: 10.7270/Q24749VQ
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50289567 (2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...) Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes				Bioorg Med Chem Lett 7: 1583-1588 (1997) Article DOI: 10.1016/S0960-894X(97)00266-7 BindingDB Entry DOI: 10.7270/Q24749VQ
					More data for this Ligand-Target Pair