BDBM50290000 CHEMBL68864::N-[2-(6-Methoxy-quinolin-4-yl)-ethyl]-butyramide
SMILES: CCCC(=O)NCCc1ccnc2ccc(OC)cc12
InChI Key: InChIKey=QPFBTHDYEIPJKI-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melatonin receptor (Homo sapiens (Human)) | BDBM50290000 (CHEMBL68864 | N-[2-(6-Methoxy-quinolin-4-yl)-ethyl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells | Bioorg Med Chem Lett 7: 2177-2180 (1997) Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50290000 (CHEMBL68864 | N-[2-(6-Methoxy-quinolin-4-yl)-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells | Bioorg Med Chem Lett 7: 2177-2180 (1997) Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R | |||||||||||
More data for this Ligand-Target Pair |