BDBM50290087 (2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-hexanoic acid hydroxyamide::CHEMBL305729

SMILES: CC(C)C[C@H]([C@@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)C(=O)N1CCCCC1

InChI Key: InChIKey=XNKSQYFVFJZMOA-HUUCEWRRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50290087 ((2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,...) Show SMILES CC(C)C[C@H]([C@@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H34N4O5/c1-13(2)11-14(17(26)23-9-7-6-8-10-23)15(16(25)21-29)12-24-18(27)20(3,4)22(5)19(24)28/h13-15,29H,6-12H2,1-5H3,(H,21,25)/t14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human gelatinase B, MMP9				Bioorg Med Chem Lett 7: 2299-2302 (1997) Article DOI: 10.1016/S0960-894X(97)00416-2 BindingDB Entry DOI: 10.7270/Q26T0MM8
					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50290087 ((2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,...) Show SMILES CC(C)C[C@H]([C@@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H34N4O5/c1-13(2)11-14(17(26)23-9-7-6-8-10-23)15(16(25)21-29)12-24-18(27)20(3,4)22(5)19(24)28/h13-15,29H,6-12H2,1-5H3,(H,21,25)/t14-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)				Bioorg Med Chem Lett 7: 2299-2302 (1997) Article DOI: 10.1016/S0960-894X(97)00416-2 BindingDB Entry DOI: 10.7270/Q26T0MM8
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50290087 ((2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,...) Show SMILES CC(C)C[C@H]([C@@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H34N4O5/c1-13(2)11-14(17(26)23-9-7-6-8-10-23)15(16(25)21-29)12-24-18(27)20(3,4)22(5)19(24)28/h13-15,29H,6-12H2,1-5H3,(H,21,25)/t14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human stromelysin-1, MMP-3				Bioorg Med Chem Lett 7: 2299-2302 (1997) Article DOI: 10.1016/S0960-894X(97)00416-2 BindingDB Entry DOI: 10.7270/Q26T0MM8
					More data for this Ligand-Target Pair