null

SMILES: CN([C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1)C(=O)c1cccs1

InChI Key: InChIKey=JCGBUUHLRXHEQS-WGSAOQKQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290212 (CHEMBL80315 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1)C(=O)c1cccs1 |wU:5.5,wD:2.1,(2.41,-5.51,;3.2,-6.86,;4.74,-6.84,;5.49,-8.17,;7.03,-8.17,;7.81,-6.84,;9.35,-6.83,;10.11,-5.49,;11.65,-5.47,;12.39,-4.11,;13.93,-4.09,;14.73,-5.4,;14,-6.74,;12.46,-6.77,;16.27,-5.37,;17.06,-6.69,;18.6,-6.66,;19.35,-5.3,;18.53,-3.99,;19.28,-2.64,;17,-4.02,;16.2,-2.71,;7.03,-5.51,;5.49,-5.51,;2.43,-8.17,;.89,-8.2,;3.2,-9.52,;4.72,-9.59,;4.58,-12.25,;3.04,-12.16,;2.34,-10.81,)| Show InChI InChI=1S/C24H31Cl2N3OS/c1-27(24(30)22-6-3-17-31-22)19-9-7-18(8-10-19)11-12-28-13-15-29(16-14-28)21-5-2-4-20(25)23(21)26/h2-6,17-19H,7-16H2,1H3/t18-,19-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290212 (CHEMBL80315 | Thiophene-2-carboxylic acid (4-{2-[4...) Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1)C(=O)c1cccs1 |wU:5.5,wD:2.1,(2.41,-5.51,;3.2,-6.86,;4.74,-6.84,;5.49,-8.17,;7.03,-8.17,;7.81,-6.84,;9.35,-6.83,;10.11,-5.49,;11.65,-5.47,;12.39,-4.11,;13.93,-4.09,;14.73,-5.4,;14,-6.74,;12.46,-6.77,;16.27,-5.37,;17.06,-6.69,;18.6,-6.66,;19.35,-5.3,;18.53,-3.99,;19.28,-2.64,;17,-4.02,;16.2,-2.71,;7.03,-5.51,;5.49,-5.51,;2.43,-8.17,;.89,-8.2,;3.2,-9.52,;4.72,-9.59,;4.58,-12.25,;3.04,-12.16,;2.34,-10.81,)| Show InChI InChI=1S/C24H31Cl2N3OS/c1-27(24(30)22-6-3-17-31-22)19-9-7-18(8-10-19)11-12-28-13-15-29(16-14-28)21-5-2-4-20(25)23(21)26/h2-6,17-19H,7-16H2,1H3/t18-,19-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair