null

SMILES: Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl

InChI Key: InChIKey=IBNGPFLSWWZTBJ-XUTJKUGGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290220 (CHEMBL430439 | N-(4-{2-[4-(2,3-Dichloro-phenyl)-pi...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl |wU:12.11,wD:15.18,(18.02,-6.23,;17.27,-7.58,;18.09,-8.9,;17.34,-10.25,;15.8,-10.29,;15.01,-8.97,;13.47,-8.99,;12.74,-10.34,;11.2,-10.37,;10.39,-9.06,;8.85,-9.08,;8.1,-10.43,;6.56,-10.44,;5.77,-11.77,;4.23,-11.77,;3.48,-10.44,;4.23,-9.11,;5.77,-9.11,;1.94,-10.45,;1.17,-11.78,;-.37,-11.79,;1.94,-13.11,;3.45,-13.1,;4.21,-14.42,;3.46,-15.76,;1.92,-15.76,;1.17,-14.43,;11.14,-7.71,;12.68,-7.68,;15.75,-7.61,;14.94,-6.31,)| Show InChI InChI=1S/C25H31Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h1-8,19,21H,9-18H2,(H,28,31)/t19-,21-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290220 (CHEMBL430439 | N-(4-{2-[4-(2,3-Dichloro-phenyl)-pi...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl |wU:12.11,wD:15.18,(18.02,-6.23,;17.27,-7.58,;18.09,-8.9,;17.34,-10.25,;15.8,-10.29,;15.01,-8.97,;13.47,-8.99,;12.74,-10.34,;11.2,-10.37,;10.39,-9.06,;8.85,-9.08,;8.1,-10.43,;6.56,-10.44,;5.77,-11.77,;4.23,-11.77,;3.48,-10.44,;4.23,-9.11,;5.77,-9.11,;1.94,-10.45,;1.17,-11.78,;-.37,-11.79,;1.94,-13.11,;3.45,-13.1,;4.21,-14.42,;3.46,-15.76,;1.92,-15.76,;1.17,-14.43,;11.14,-7.71,;12.68,-7.68,;15.75,-7.61,;14.94,-6.31,)| Show InChI InChI=1S/C25H31Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h1-8,19,21H,9-18H2,(H,28,31)/t19-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290220 (CHEMBL430439 | N-(4-{2-[4-(2,3-Dichloro-phenyl)-pi...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl |wU:12.11,wD:15.18,(18.02,-6.23,;17.27,-7.58,;18.09,-8.9,;17.34,-10.25,;15.8,-10.29,;15.01,-8.97,;13.47,-8.99,;12.74,-10.34,;11.2,-10.37,;10.39,-9.06,;8.85,-9.08,;8.1,-10.43,;6.56,-10.44,;5.77,-11.77,;4.23,-11.77,;3.48,-10.44,;4.23,-9.11,;5.77,-9.11,;1.94,-10.45,;1.17,-11.78,;-.37,-11.79,;1.94,-13.11,;3.45,-13.1,;4.21,-14.42,;3.46,-15.76,;1.92,-15.76,;1.17,-14.43,;11.14,-7.71,;12.68,-7.68,;15.75,-7.61,;14.94,-6.31,)| Show InChI InChI=1S/C25H31Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h1-8,19,21H,9-18H2,(H,28,31)/t19-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290220 (CHEMBL430439 | N-(4-{2-[4-(2,3-Dichloro-phenyl)-pi...) Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl |wU:12.11,wD:15.18,(18.02,-6.23,;17.27,-7.58,;18.09,-8.9,;17.34,-10.25,;15.8,-10.29,;15.01,-8.97,;13.47,-8.99,;12.74,-10.34,;11.2,-10.37,;10.39,-9.06,;8.85,-9.08,;8.1,-10.43,;6.56,-10.44,;5.77,-11.77,;4.23,-11.77,;3.48,-10.44,;4.23,-9.11,;5.77,-9.11,;1.94,-10.45,;1.17,-11.78,;-.37,-11.79,;1.94,-13.11,;3.45,-13.1,;4.21,-14.42,;3.46,-15.76,;1.92,-15.76,;1.17,-14.43,;11.14,-7.71,;12.68,-7.68,;15.75,-7.61,;14.94,-6.31,)| Show InChI InChI=1S/C25H31Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h1-8,19,21H,9-18H2,(H,28,31)/t19-,21-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair