null

SMILES: O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccn2)CC1)c1cccs1

InChI Key: InChIKey=ZSOAASMDFMEZPH-WGSAOQKQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50290229 (CHEMBL78406 | PD-137557 | Thiophene-2-carboxylic a...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccn2)CC1)c1cccs1 |wU:3.2,wD:6.6,(5.88,-2.66,;5.57,-4.16,;6.69,-5.2,;8.16,-4.71,;8.48,-3.22,;9.95,-2.75,;11.09,-3.78,;12.56,-3.32,;13.68,-4.36,;15.15,-3.88,;16.29,-4.92,;17.74,-4.46,;18.08,-2.96,;16.95,-1.92,;15.48,-2.38,;19.55,-2.49,;20.67,-3.53,;22.14,-3.08,;22.47,-1.57,;21.33,-.52,;19.87,-.99,;10.76,-5.29,;9.3,-5.75,;4.09,-4.64,;3.62,-6.1,;2.08,-6.1,;1.62,-4.64,;2.85,-3.74,)| Show InChI InChI=1S/C22H30N4OS/c27-22(20-4-3-17-28-20)24-19-8-6-18(7-9-19)10-12-25-13-15-26(16-14-25)21-5-1-2-11-23-21/h1-5,11,17-19H,6-10,12-16H2,(H,24,27)/t18-,19-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50290229 (CHEMBL78406 | PD-137557 | Thiophene-2-carboxylic a...) Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccn2)CC1)c1cccs1 |wU:3.2,wD:6.6,(5.88,-2.66,;5.57,-4.16,;6.69,-5.2,;8.16,-4.71,;8.48,-3.22,;9.95,-2.75,;11.09,-3.78,;12.56,-3.32,;13.68,-4.36,;15.15,-3.88,;16.29,-4.92,;17.74,-4.46,;18.08,-2.96,;16.95,-1.92,;15.48,-2.38,;19.55,-2.49,;20.67,-3.53,;22.14,-3.08,;22.47,-1.57,;21.33,-.52,;19.87,-.99,;10.76,-5.29,;9.3,-5.75,;4.09,-4.64,;3.62,-6.1,;2.08,-6.1,;1.62,-4.64,;2.85,-3.74,)| Show InChI InChI=1S/C22H30N4OS/c27-22(20-4-3-17-28-20)24-19-8-6-18(7-9-19)10-12-25-13-15-26(16-14-25)21-5-1-2-11-23-21/h1-5,11,17-19H,6-10,12-16H2,(H,24,27)/t18-,19-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
					More data for this Ligand-Target Pair