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BDBM50290344 CHEMBL420978::Carbonic acid ethyl ester 1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-ylmethyl ester

SMILES: CCOC(=O)OCc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1

InChI Key: InChIKey=FWWYIMUZFVHATP-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290344
PNG
(CHEMBL420978 | Carbonic acid ethyl ester 1-(4-fluo...)
Show SMILES CCOC(=O)OCc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H27FN2O3/c1-2-33-28(32)34-18-26-25-12-6-10-21(17-20-9-5-8-19-7-3-4-11-24(19)20)27(25)31(30-26)23-15-13-22(29)14-16-23/h3-5,7-9,11,13-16,21H,2,6,10,12,17-18H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair