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BDBM50290347 CHEMBL84715::[1-(4-Fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-yl]-carbamic acid methyl ester

SMILES: COC(=O)Nc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1

InChI Key: InChIKey=BOLRTTJZBPFWAF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290347   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290347
PNG
(CHEMBL84715 | [1-(4-Fluoro-phenyl)-7-naphthalen-1-...)
Show SMILES COC(=O)Nc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1
Show InChI InChI=1S/C26H24FN3O2/c1-32-26(31)28-25-23-11-5-9-19(16-18-8-4-7-17-6-2-3-10-22(17)18)24(23)30(29-25)21-14-12-20(27)13-15-21/h2-4,6-8,10,12-15,19H,5,9,11,16H2,1H3,(H,28,29,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 1.57E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair