new BindingDB logo
myBDB logout

BDBM50290350 CHEMBL315817::Diethyl-[1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-ylmethyl]-amine

SMILES: CCN(CC)Cc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1

InChI Key: InChIKey=MKFBBNGWCLZUCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290350   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290350
PNG
(CHEMBL315817 | Diethyl-[1-(4-fluoro-phenyl)-7-naph...)
Show SMILES CCN(CC)Cc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1
Show InChI InChI=1S/C29H32FN3/c1-3-32(4-2)20-28-27-14-8-12-23(19-22-11-7-10-21-9-5-6-13-26(21)22)29(27)33(31-28)25-17-15-24(30)16-18-25/h5-7,9-11,13,15-18,23H,3-4,8,12,14,19-20H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 1.38E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair